American Association for the Study of Liver Disease, Simplified HCV Treatment, without and with Compensated Cirrhosis

Simplified HCV Treatment Algorithm for Treatment-Naive Adults With Compensated Cirrhosis Who Is NOT Eligible for Simplified Treatment Patients who have any of the following characteristics: Current or prior episode of decompensated cirrhosis, defined as Child-Turcotte-Pugh (CTP) score ≥7 (ascites, hepatic encephalopathy, total bilirubin >2.0 mg/dL, albumin ≤3.5 g/dL, or INR ≥1.7) Prior hepatitis C treatment End-stage renal disease (ie, eGFR <30 mL/min/m2) (see Patients with Renal Impairment section) HIV and/or HBsAg positive Current pregnancy Known or suspected hepatocellular carcinoma Prior liver transplantation (see HCV guidance for treatment recommendations for these patients)