What is Xylazine?
− A non-opioid agent that the FDA originally approved in 1972 as a sedative and analgesic for use in veterinary medicine (not FDA approved for use in humans)
− Acts as a central alpha-2-adrenergic receptor agonist in the brainstem (like clonidine)
o Rapid decrease in the release of norepinephrine and dopamine in the central nervous system (CNS)
o May also bind to other CNS receptors
Alcohol Use in Adolescence Adolescents use alcohol more than any other drug, including tobacco and marijuana. Binge drinking (consuming five or more drinks on one occasion for males, or four or more drinks for females) is the most commonly reported—and most dangerous—way that adolescents consume alcohol.1 Adolescents who drink alcohol are more likely to experience negative consequences such as injury …
Sample Tip Sheet content: Choose one or a small number (< 5) of behaviors to address. In most cases, group “substance use” as a single behavior Set clear expectations that your child(ren) does not have permission to use substances. Use clear language, avoid euphemisms or generalizations: “You do not have my/our permission to …
Boston Children’s Hospital Adolescent Substance Use & Addiction Program TIP Sheets Read More »
