Best Practice of the Use of XR Bupenorphine and Naltrexone

The presenter will explore the promising and best practices on the use of XR Buprenorphine and naltrexone. The ways the medications can be delivered and practical issues of certification in the SUBLOCADE REMS program, storage, and administration will be discussed.

Learning objectives:

  1. Assess which patients are appropriate for treatment with the extended release (XR) formulation of Buprenorphine and Naltrexone.
  2. Familiarize with the induction and monitoring processes for XR Buprenorphine and XR Naltrexone. Familiarize with delivery, storage, and administration (including certification in the Sublocade REMS Program).

Prescribing clinicians


John Mariani, MDJohn Mariani, MD is an Associate Professor of Clinical Psychiatry at the College of Physicians and Surgeons of Columbia University and a Research Psychiatrist at the New York State Psychiatric Institute. After receiving his medical degree from the New York University School of Medicine and completing his psychiatry residency at the Beth Israel Medical Center in New York City, where he served as Chief Resident, Dr. Mariani began a two-year addiction psychiatry research fellowship at Columbia University. In 2005, he joined the faculty of the Division on Substance Abuse as a Research Psychiatrist. Under the mentorship of Dr. Frances Levin, he has remained active in clinical research and is the recipient of a K-23 Mentored Patient-Oriented Research Career Development Award from the National Institute on Drug Abuse. Currently, Dr. Mariani is the Director of Columbia University’s Substance Treatment and Research Service (STARS). His research has primarily focused on investigating novel pharmacotherapies for addictive disorders.

Continuing Medical Education

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Maine Medical Education Trust and CCSME. The Maine Medical Education Trust is accredited by the Maine Medical Association Committee on Continuing Medical Education and Accreditation to provide continuing medical education for physicians.

Contact Hours
  • 1 contact hour for social workers, licensed clinical professional counselors, and behavioral health professionals.
  • 1 Category I contact hour for psychologists are provided. CCSME is a pre-approved sponsor and provider of Professional Education Activities for Psychologists.
  • 1 contact hour CHES. CCSME is a designated provider of continuing education contact hours (CECH) in health education by the National Commission for Health Education Credentialing, Inc.
  • 1 contact hour pending for alcohol and drug counselors from the board of alcohol and drug counselors

Opioid Response Network STR-TA/SOR-TAFunding for this initiative was made possible (in part) by grant nos. 6H79TI080816 and 1H79TI083343 from SAMHSA. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


May 04 2022


12:00 pm - 1:00 pm



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